ANTI HERPES
VEGETAL NON-DRUG EXTRACT
MADE FROM SPONDIAS MOMBIN
Spondias Mombin is a fruit tree having habitat in Brazil and several other tropical forests in the world. Its fruits are highly appreciated by local people and using it to make fruit or ice cream.
This plant is part of the "Living Pharmacy"
program developed by the Laboratory of Natural Products - Federal University
of Ceara, Brazil, (UCB), a project aiming to teach local people how to
cultivate and correctly use traditional medicinal plants.
Infusion of its leaves has been used for a long time without any reports of
any collateral effects, due to its antivirotic activity, mainly against the
herpes virus!
In 1991, researchers at Antuerpia
University in Belgium isolated from branches and leaves of the plant, Geraniin
(1) and Balloyl Geraniin (2), two ellagitannins with antivirotic activity
against the virus Herpes Simplex, Type 2 and Coxsackie B2, confirming previous
studies done by Fukuchi, et al., which have shown the anti-herpes activity of
Geraniin (1) and related tannins.
The activity of this substance was shown to be in the order of 50
micrograms / ml. More recently, the same Belgium researchers isolated from the
leaves and stems of this plant the Caffeic ester of the (+) Allo-hydroxycitric
acid (3) and the Butyl ester of Chlorogenic acid.
The first compound presented an anti-virotic action against Coxsackie B2 and
the second compound has shown activity against the Herpes Simplex 1 virus, in
the concentration of 100 micrograms / ml. The activity of the photochemical
hydro-alcoholic extract of the leaves and stems of the Spondais Mombin,
continues to be evaluated by researchers at The Laboratory of Natural Products
- Federal University of Ceara, Brazil, who are isolating known substances and
searching for new compounds with similar antivirotic activity.
The ANTI HERPES FORMULATION
The antivirotic activity of this plant is
potentiated probably by the synergistic action arriving from the different
types of substances present in its leaves and stems, the tannins being the
most important ones.
Another substance also could be present, increasing the anti-virotic
efficiency of the plant. Therefore, instead of isolating each one and testing
them, the researchers of the Technological Development Park- PADATEC at UFC,
developed a hydroalcoholic extract, from finely ground leaves and stems of
this plant, is to be used orally by people with labial and genital Herpes.
PACKAGING
EXTRACT - Dropper bottles with 59 ml (2 fl oz) of hydroalcoholic extract of
Spondias Mombin. Each ml contains 10 mg of dry extract, 0.07 ml Ethyl alcohol
and 0.30 ml of distilled water.
SUGGESTED USES:
CAUTION: Keep out of reach of children! Do not use if you are pregnant!
In the event of new outbreak all the
treatment should be done again. We always recommend the client to visit
and talk to their doctor.
Although there are no reports of collateral effects of this product, there is no guarantee that can be assured for allergic reactions in hypersensitive persons.
Discontinue use if any allergic reaction is
detected. Always consult your health care professional.
REFERENCES
1) F.J.A. Mats, " Farmacias Vivas",Ed. UFC, 2a. Ed., Forteleza
(1994)
2) J. Corthort, L.A.Pieters, M.Claeys, D.A. Vanden Berghe and A.J. Vlietinck,"Antiviral
Ellagitannins from Spondias Mombin", Phytochemistry, 30, 1190, (1990).
3) K. Fukuchi, H. Sakagami, T. Okuda, T. Hatano, S. Tanum, K. Kitajima, Y.
Inoue, S. Inoue, S. Ichikawa, M. Nonoyama and k. Konno, Antiv. Res. 11, 285
(1989).
4) J. Corthout, L.A.PIETERS, M.CLAEYS, D.A. Vanden Berghe and A.J. Vlietinck,
"Antiviral Caffeoyl; Estersfrom Spondias Mombin", Phytochemistry,
31, 1979 (1992).
by José Claret Theodoro da Silva
Pharmaceutical Manager
Extra:
Article: ...Recently a series of such new alkenyl phenolic acids have been reported to occur in Spondias mombin L., the leaves of which are used as antimicrobial agents and in folk medicine for various purposes. These unsaturated phenolic acids showed varied biological activities such as antiviral against Coxsackie B2 and Herpes simplex type 1 viruses; antibacterial against Bacillus cereus, Streptococcus pyogenes and Mycobacterium fortuitum and molluscicidal, against the snail Biomphalaria glabrata...
Abstrats: others articles
